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This booklet explains what histology independent therapies are, how they are given and possible side effects. It includes information about genes and gene changes and how they relate to HITs. It also has information on 2 HITs drugs called larotrectinib and entrectonib and where to get further support.
This booklet has been produced in partnership with NHS England (Accelerated Access Collaborative), Cancer Research UK, Teenage Cancer Trust and Sarcoma UK.
Download PDFKeywords: MAC19456_E01_R, histology independent therapy, HITs, larotrectinib, entrectinib, genes, gene changes
This resource was last revised in July 2025.
